The Laboratory of Computational Biology is an interdisciplinary group of scientists who study biological processes via computer simulation. It is part of the Biochemistry and Biophysics Center Division of Intramural Research National Heart, Lung, and Blood Institute in the National Institutes of Health. The laboratory is led by Dr. Bernard R. Brooks.
The Laboratory is organized into three sections and one facility, each led by a principal investigator. A brief overview of their work is given here, and you can find out more in the web pages for each section.
Computational Biophysics Section
Dr. Bernard Brooks
The Computational Biophysics Section (CBS) consists of researchers who both develop simulation and modeling techniques and apply them towards the study of problems of biological significance. Techniques employed include; molecular dynamics, quantum and molecular mechanics, ab initio analysis of small molecule structures, molecular modeling, and electron microscopy image analysis.
Membrane Biophysics Section
Dr. Richard Pastor
The Membrane Biophysics Section (MBS) is a group of researchers who use diverse theoretical methods combined with high performance computing to investigate the properties of lipid membranes and related molecular assemblies. The section operates under the direction of Dr. Richard Pastor; the group joined the NIH/NHLBI Laboratory of Computational Biology (LCB) in 2006, after 20 years in FDA/CBER's Laboratory of Biophysics.
High Performance Computing Section
Dr. Bernard Brooks
The High Performance Computing Section (HPCS) maintains and supports all the infrastructure of hardware and software of the LoBoS cluster that allow researchers of the laboratory to use high performance computing to investigate biological processes. The section operates under the direction of Dr. Bernard Brooks.